How AI is Unlocking the Cure for Thousands
of Illnesses, with Dr. David Fajgenbaum,

Dr. David Fajgenbaum, co-founder of Every Cure and a tenured professor at Penn Medicine, has lived through what most patients can’t imagine: battling Castleman disease. This rare condition nearly killed him five times. His survival came from an unexpected breakthrough: a repurposed drug, sirolimus, that put him into long-term remission.

Now, David is using his personal story to fuel a global movement: finding new treatments for deadly diseases by repurposing existing drugs. Through Every Cure, he and his team are leveraging AI in medicine to evaluate 4,000 approved drugs across 18,000 human diseases, uncovering life-saving opportunities that were previously hidden in plain sight.

In this episode of FOMO Sapiens, David explains:

• Why cures aren’t being hidden, but ignored because they’re “unprofitable.”
  
• How Every Cure’s AI-driven platform identifies promising drug repurposing matches at lightning speed.
  
• Why this model delivers a 130x ROI compared to traditional drug development.
  
• The storytelling and leadership lessons he’s learned as both a patient and a scientist.

Whether you’re passionate about healthcare, innovation, or leadership, David’s story is proof that hope can be turned into action and that the answers to our greatest challenges may already be within reach.

Meet David Fajgenbaum:

David Fajgenbaum, MD, MBA, MSc, is co-founder & President of Every Cure and one of the youngest tenured professors ever at Penn Medicine. He is also battling a deadly disease as a patient and alive thanks to a repurposed treatment he discovered and described in his bestselling memoir Chasing My Cure. He has advanced 13 more repurposed treatments for cancers and rare diseases and co-founded Every Cure to unlock more hidden cures, which has received over $100M from ARPA-H and TED’s Audacious Project.

He has been profiled by The New York Times, Good Morning America, TODAY, and Forbes 30 Under 30 and awarded the Atlas Award along with then-Vice President Joe Biden, the Philadelphia Citizen of the Year award, and named to TIME100 Health. David earned a BS from Georgetown University, an MSc from Oxford University, an MD from the University of Pennsylvania, and an MBA from Wharton.